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BIND Therapeutics Announces Initiation of Clinical Studies with Accurin AZD2811 in Solid Tumors

CAMBRIDGE, Mass.–(BUSINESS WIRE)– BIND Therapeutics, Inc. (NASDAQ: BIND), a clinical-stage nanomedicine company developing targeted and programmable therapeutics called Accurins™, today announced that AstraZeneca (NYSE: AZN) has initiated patient dosing in a phase 1 clinical trial of the Accurin AZD2811 drug candidate in solid tumors. AZD2811, a novel, selective inhibitor of Aurora B kinase that has been shown to be active in both solid and hematological tumors in preclinical models, is the second Accurin candidate to enter clinical development. The phase 1 trial is enrolling patients with advanced solid tumors, including patients with small cell lung cancer, and is being conducted by AstraZeneca under the companies’ 2013 collaboration agreement with BIND managing all chemistry, manufacturing and control activities. BIND earned a $4.0 million clinical milestone for dosing of the first patient.

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