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Arena Pharmaceuticals Initiates a Phase 2 Clinical Trial of APD334, its S1P1 Receptor Modulator for Autoimmune Diseases

SAN DIEGO, July 29, 2015 /PRNewswire/ — Arena Pharmaceuticals, Inc. (NASDAQ: ARNA) announced today the initiation of patient screening in a Phase 2 proof-of-concept clinical trial of APD334 in ulcerative colitis. Discovered by Arena, APD334 is an oral, investigational, Sphingosine 1-Phosphate Subtype 1 (S1P1) receptor modulator with therapeutic potential in ulcerative colitis as well as other autoimmune diseases.

“Important goals of pharmacotherapy for ulcerative colitis are to induce and maintain remission while improving the patient’s quality of life, and, based on the results from our Phase 1 program, we believe APD334 has the potential to achieve these goals,” said Jack Lief, Arena’s President and Chief Executive Officer. “In addition to ulcerative colitis, we believe APD334 could have utility for a variety of autoimmune diseases.”

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