Multi-center collaboration aims to advance neutralizing antibody research from preclinical to clinical trials
Seattle, WA, March 10, 2013 — Seattle BioMed today announced that it has received a seven year Integrated Preclinical/Clinical AIDS Vaccine Development (IPCAVD) grant from the National Institute of Allergy and Infectious Diseases (NIAID) to develop a vaccine that would elicit broadly neutralizing antibodies against HIV-1. Seattle BioMed will lead a consortium comprised of the Rockefeller University, the University of Washington, Seattle Children’s Hospital and the Fred Hutchinson Cancer Research Center. The investigators will receive $9.8 million over seven years to fund the initial phase of the project which will include the optimization and preclinical evaluation of two vaccine candidates. The second phase of the project will include the production of these vaccines according to current Good Manufacturing Practices (cGMP) and the evaluation of their safety and immunogenicity in a Phase I clinical trial.