While RNA therapeutics have the potential to potently modulate disease causing genes to treat patients with serious disorders, delivery of this therapeutic class to tissues outside of the liver remains a challenge.  Oligonucleotide therapeutics, such as short interfering RNA (siRNA), are rapidly cleared by the kidneys before they can reach the diseased tissue, and the […]

Antibody (Ab) therapeutics are the most prominent class of drugs today. Developed to deliver cytotoxic payloads to tumors, these therapies are evolving to provide new, next-generation conjugates and treat various diseases beyond cancer. “Among the emerging antibody drugs, those in the non-traditional formats are becoming more and more popular, such as bispecific antibodies and antibody-drug […]

New COVID-19 boosters are rolling out, but the US still leads the world in daily pandemic deaths. At the same time, we’re one of over 80 countries (1) struggling to control monkeypox in regions where it is not endemic. Even polio is waging a comeback. Though these diseases are very different, this confluence of viruses […]