The fight against Alzheimer’s disease remains one of medical science’s more demanding challenges. Progress has been slow and often frustrating, as one drug after another has failed to live up to its promise in human clinical trials. But those failures, along with technological advances in brain-scanning, have helped stimulate new avenues of research — including […]

After getting off a $66 million series B round in September last year, hereditary angioedema (HAE) specialist Pharvaris has taken on a seasoned HAE developer to help lead its pipeline. The startup has nabbed former Takeda/Shire exec Peng Lu, M.D., Ph.D., as its chief medical officer; Lu comes from Shire after it has been subsumed […]

Patients with metastatic colorectal cancer (mCRC) treated with the combination of the investigational polo-like kinase 1 inhibitor, onvansertib, plus FOLFIRI (Irinotecan, Fluorouracil [5-FU], and folinic acid [leucovorin]), and bevacizumab (Avastin) had a 100% clinical benefit rate at 8 weeks by radiographic response in a phase Ib study presented at the 2020 Gastrointestinal Cancers Symposium. Data […]