As monkeypox spreads across dozens of countries, one of the few biotechs publicly working on a new vaccine for the virus is gearing up to enter the clinic in the first half of next year. The study of Tonix Pharmaceuticals’ live virus vaccine will occur at Kenya Medical Research Institute, or KEMRI, in the East […]

Tonix Pharmaceuticals Holding Corp shares are soaring Monday after the World Health Organization (WHO) declared monkeypox a public health emergency of global concern. Tonix’s TNX-801 is being developed as a vaccine to protect against monkeypox. “We already have very compelling data showing protection of monkeys against the lethal challenge of monkeypox,” Tonix CEO Seth Lederman said Monday on Benzinga’s YouTube show […]

With a Phase IIb palmoplantar pustulosis (PPP) trial underway, Aristea Therapeutics is looking ahead to a potential Phase III study. But different primary endpoint preferences between regulators in the US and Europe could complicate its trial design process. Aristea is testing its small molecule RIST4721 in an ongoing 156-patient Phase IIb trial in PPP (NCT05194839), […]